Vitamin D (also called “calciferol”) is a fat-soluble vitamin that occurs naturally in several foods, is added to others, and is available as a dietary supplement. It is also produced endogenously when sunlight’s ultraviolet (UV) rays hit the skin and trigger vitamin D synthesis.
Vitamin D from sunlight, food, and supplements is biologically inert and must undergo two hydroxylations in the body to be activated. The first hydroxylation that occurs in the liver converts vitamin D to 25-hydroxyvitamin D [25(OH)D], also known as “calcidiol.” The second hydroxylation takes place primarily in the kidney and forms the physiologically active 1,25-dihydroxy vitamin D [1,25(OH)2D], also known as “calcitriol.”
The oral supplement is usually the active form of Calcitriol. Unfortunately, the absorption of the supplement by oral intake varies from one individual to another.
Vitamin D in Vitamin D is a fat-soluble vitamin that promotes the absorption of calcium and phosphate from the gut to benefit bone health and the immune system.
Vitamin D is available in two forms:
Vitamin D2 (ergocalciferol) – present in plants.
Vitamin D3 (cholecalciferol) – is synthesized over time when we expose our skin to sunlight.
However, because vitamin D is volatile, it is not always easy for our body to absorb the necessary amount. A study shows that 1 in 4 people in our country is vitamin D deficient. The functional and integrative medicine societies recommend doubling the standard lab value. If you consider this, almost three out of four individuals in the USA are deficient.
Benefits of vitamin D in West Palm Beach Gardens:
– Supports bone development
– It contributes to bone strength and prevents loss of bone mass
– Relieves bone, muscle pain, and inflammation symptoms
– It strengthens the immune system
– Lowers cholesterol and blood pressure
– Improves mood and reduces anxiety
– It reduces the risk of heart disease, obesity, and cognitive decline
When should you get a vitamin D injection in West Palm Beach Gardens?
Vitamin D is naturally present in foods such as cheese and fatty fish or foods fortified with vitamin D such as dairy products and cereals. However, if you can’t get the recommended daily allowance of vitamin D from dietary sources or sunlight, vitamin D supplementation is the only way. You can opt for a vitamin D supplement or injection, and I recommend starting both as soon as possible. You can switch to the oral supplement form only when you reach the target level. If the level starts to decline, you can either begin IM injection again or double your supplement intake to return to the desired value.
Vitamin D treatment usually involves three intramuscular injections per year, given at set intervals, but the dosage depends on the patient’s health, baseline vitamin D levels, and calcium levels. The vitamin D injection consists of 50,000 IU to 100,000 IU, promotes intestinal calcium absorption, and maintains adequate serum calcium and phosphate concentrations. This level will allow normal bone mineralization and prevent hypocalcemic tetany (involuntary muscle contractions leading to spasms and convulsions). Vitamin D is also required for bone growth.
Without enough vitamin D, bones can become thin, brittle, or deformed. Sufficient vitamin D prevents rickets in children and osteomalacia in adults. Along with calcium, vitamin D helps protect older adults from osteoporosis.
Vitamin D has other bodily roles, including reducing inflammation and modulating processes such as cell growth, neuromuscular and immune function, and glucose metabolism.
Serum 25(OH)D concentration is the primary indicator of vitamin D status. It reflects endogenously produced vitamin D and vitamin D obtained from food and supplements.
Researchers have not definitively identified serum 25(OH)D concentrations associated with deficiency (e.g., rickets), adequacy for bone health, and overall health. A Vitamin D concentration of less than 30 nmol/L is considered a deficiency, and some people risk deficiency at 30 to 50 nmol/L (12–20 ng/mL). Levels of 50 nmol/L (20 ng/mL) or more are sufficient for most people. In contrast, the Endocrine Society stated that for clinical practice, a serum 25(OH)D concentration greater than 75 nmol/L (30 ng/mL) is necessary to maximize the effect of vitamin D on calcium, bone, and muscle metabolism.
Serum concentrations greater than 125 nmol/L (50 ng/mL) might be associated with adverse effects.
Optimal serum concentrations of 25(OH)D for bone and overall health have not been established, and they are likely to vary by life stage, race, ethnicity, and physiological measure. Furthermore, although 25(OH)D levels rise in response to increased vitamin D intake, the relationship is non-linear. The degree of increase varies with, for example, baseline serum levels and duration of supplementation. This is why staying on the safe side and close to the standard value’s upper limit is essential.
Vitamin D is fat Soluble. Excesses can’t be excreted in urine and can lead to a high toxic level. It is essential to monitor your blood level from time to time to make sure you maintain a healthy concentration.
Vitamin D is the precursor to immune-defending cytokines and helps defend the body against various infections.
Vitamin D has antioxidant properties. Combining Vitamin D with Glutathione injection is a powerful antioxidant combo.
A deficiency of vitamin D leads to severe rickets in children and bone resorption in adults.
Dosing and administration :
Oral is effective and economical but correcting a low value with oral intake is a slow process.
Recommended Intake :
Recommendations for vitamin D intake vary by age, ethnicity, and gender.
Sufficient intake at this level is assumed to ensure nutritional adequacy.
One mcg of vitamin D equals 40 IU. Although sunlight is the primary source of vitamin D for some people, the FNB based the vitamin D RDA on the assumption that people have only minimal exposure to sunlight.
Many countries worldwide and some professional societies have slightly different guidelines for vitamin D intake. These differences result from an incomplete understanding of vitamin D’s biology and clinical implications. For example, the Endocrine Society states that to maintain serum 25(OH)D levels above 75 nmol/L (30 ng/mL), adults may need at least 37.5 to 50 mcg (1,500–2,000 IU) of the supplemental vitamin per day.
Sources of Vitamin D
Few foods naturally contain vitamin D. The best sources include fatty fish (such as trout, salmon, tuna, and mackerel) and fish liver oils. An animal’s diet affects the amount of vitamin D in its tissues. Studies show that 25(OH)D appears to be approximately five times more effective than the parent vitamin for increasing serum 25(OH)D concentrations. One study found that when the 25(OH)D content of beef, pork, chicken, turkey, and eggs are considered, the total amount of vitamin D in the food is 2 to 18 times greater than the amount in the parent vitamin.
Fortified foods provide the majority of vitamin D in the American diet. For example, nearly all milk in the US is voluntarily fortified with approximately three mcg/cup (120 IU), usually in vitamin D3. Plant-based milk alternatives (such as drinks made from soy, almond, or oat) are often fortified with similar amounts of vitamin D as fortified cow’s milk (about three mcg [120 IU]/cup). Ready-made breakfast cereals often contain added vitamin D, like some brands of orange juice, yogurt, margarine, and other food products.
Most people in the world meet at least part of their vitamin D needs through exposure to sunlight. Season, time of day, length of day, cloud cover, smog, skin melanin content, and sunscreen are among the factors that affect UV exposure and vitamin D synthesis. Older people and people with dark skin can produce less vitamin D from sunlight. UVB radiation does not penetrate glass, so exposure to sunlight indoors through a window does not produce vitamin D.
Factors influencing UV exposure, individual responsiveness, and uncertainty about the amount of sunlight needed to maintain adequate vitamin D levels make it challenging to guide how much sunlight is required for sufficient vitamin D synthesis. For example, some professional organizations and vitamin D researchers suggest that about 5–30 minutes of daylight, especially between 10:00 a.m. and 4:00 p.m., either daily or at least twice a week on the face, arms, hands, and legs without sunscreen usually results in the sound synthesis of vitamin D.
The moderate use of commercial tanning beds, which emit 2% to 6% UVB radiation, is also effective [13,29].
However, despite the importance of the sun for vitamin D synthesis, it is prudent to limit skin exposure to sunlight and UV radiation from tanning beds. UV radiation is a carcinogen, and exposure to UV radiation is the most common preventable cause of skin cancer. However, in practice, people usually don’t apply enough sunscreen, don’t cover all of their sun-exposed skin, or don’t apply sunscreen regularly. Their skin probably synthesizes some vitamin D, even with typically used amounts of sunscreen.
Dietary supplements may contain vitamins D2 or D3. People who avoid all animal products can contact supplement manufacturers and ask about their sourcing and processing practices.
Vitamins D2 and D3 increase serum 25(OH)D levels and appear to have the same ability to treat rickets. In addition, most of the steps in the metabolism and action of vitamins D2 and D3 are identical. However, most evidence shows that vitamin D3 increases serum 25(OH)D levels to a greater extent and maintains these higher levels longer than vitamin D2, even though both forms are well absorbed in the gut.
Vitamin D Intake and status
Most people in the United States consume less than the recommended amount of vitamin D. An analysis of data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) found that the average daily intake of vitamin D from foods and beverages was 5.1 mcg (204 IU ) in men, 4.2 mcg (168 IU) in women and 4.9 mcg (196 IU) in children aged 2–19 years. NHANES data from 2013–2016 showed that 92% of men, more than 97% of women, and 94% of people aged one year and older consumed less than the EAR of 10 mcg (400 IU) of vitamin D from food and drink.
An analysis of 2015–2016 also showed that 28% of all individuals aged two years and older in the United States used a vitamin D supplement. Total vitamin D intake was three times higher with supplementation than with diet alone; the average intake from food and beverages alone for individuals aged two and older was 4.8 mcg (192 IU) but increased to 19.9 mcg (796 IU) when dietary supplements were included.
Some people take very high doses of vitamin D supplements. In 2013–2014, an estimated 3.2% of the US adult population took supplements containing 100 mcg (4,000 IU) or more of vitamin D.
What are vitamin D3 injections?
We deliver vitamin D3 by intramuscular injection in West Palm Beach Gardens. As the name suggests, the bullet goes into the muscles, which means that vitamin D3 immediately enters the bloodstream for maximum absorption.
At Beverly Hills Wellness Center and Med Spa in West Palm Beach, we start by cleaning the injection site, which is usually the deltoid muscle in the arm. We inject vitamin D and gently apply pressure to the area before covering it with gauze or a bandage. Some people may experience a little discomfort after the shot, but it should go away soon, and you’re good to go.
Benefits and uses of vitamin D3 injections
These injections can improve your well-being because vitamin D is essential to the body. Potential benefits include:
Vitamin D helps prevent brittle and weak bones – and reduces the risk of osteoporosis that can occur as a result – by allowing the body to absorb calcium to build bones. Too little vitamin D can cause bone pain and muscle weakness in a condition called osteomalacia.
A healthy heart
Vitamin D can provide essential support in maintaining healthy blood vessels (which can reduce high blood pressure) and lowering cholesterol (to reduce the risk of atherosclerosis, the buildup of plaque on the walls of blood vessels).
A responsive immune system
Vitamin D can help support immunity by warding off bacteria that can cause colds, flu, or other illnesses. It may also be effective in reducing the symptoms of inflammation caused by autoimmune diseases.
If you struggle with mood disorders such as depression, vitamin D can help; some research suggests a link between low levels of vitamin D in the blood and symptoms of depression.
Some scientists have discovered that the brain has many vitamin D receptors, essential for developing children’s brains and maintaining cognitive function throughout life.
Diabetes and weight loss support
Low levels of vitamin D are associated with obesity and diabetes. Addressing vitamin D deficiency can help manage diabetes symptoms and boost weight loss efforts.
There are many benefits of vitamin D, and some people are better placed to take advantage of them, especially those who are vitamin D deficient.